Gender should not be a relevant criteria.

What kind of connection can I make from Calvin and Hobbes?

That’s the setup. Here’s the payoff:

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Girls need protection from the actions of adults. Boys don’t need that protection because they’re tougher and can handle anything. Even a scalpel to the genitals, right?

Yes, I understand the humor, but I don’t find the extreme version of this thinking funny or compelling. Believing that the recipient’s gender determines the acceptability of a specific action is indefensible sexism. Equality considers human beings, not different standards based on whether the person has a penis or a vagina. This is as true with circumcision as it is with equal pay.